CDH1 and neoplasm: Thus, alterations in the expression as well as in the structure of E-cadherin and catenins have been linked to tumour progression, tumour cell invasion and metastasis formation in breast, intestine and prostate cancers (Birchmeier and Behrens, 1994; Mareel et al, 1997; Christofori and Semb, 1999; Beavon, 2000).