Only cytoplasmic expression of ADAM9 and tumour grade were found to be independent prognostic factors for poor overall survival (cytoplasmic ADAM9: HR=2.85; 95% CI: 1.21–6.71, P<0.05; tumour grade: HR=4.81; 95% CI: 2.43–9.52; P<0.01) (Table 3). This evidence concerns the gene ADAM9 and neoplasm.