Following the observation by Xu et al (2001) that prostein expression is regulated by androgens, the androgen-responsive PCa cell line LNCaP 1740 was grown in medium containing FCS that was depleted of androgens by charcoal stripping or in the same stripped medium supplemented with the synthetic androgen R1881 and then used for the quantification of prostein transcripts. The gene discussed is SLC45A3; the disease is posterior cortical atrophy.