CDH13 and colorectal cancer: Zheng et al (2001) reported previously that the partial methylation pattern was associated with relatively low levels of p14ARF in colorectal cancer cell lines. p14ARF mRNA was expressed at extremely low levels in fully methylated cell lines. p14ARF expression in the partial methylated LoVo cell line was intermediate. Moreover, partial methylation of p14ARF was the most common pattern observed in primary colorectal cancers. Taken together, it was suggested that the level of CDH13 gene expression might be also controlled by methylation in colorectal cancers.