Furthermore, several recent reports have suggested that tumour derived expression of VEGF-C and VEGF-D may have prognostic value as indicators of metastatic spread in some prevalent human cancers (White et al, 2002a; Kishimoto et al, 2003; Nakamura et al, 2003a, 2003b; Schietroma et al, 2003; Yokoyama et al, 2003). The gene discussed is VEGFD; the disease is neoplasm.