Lymphatic capillary density (mm−2), as determined by immunohistochemical staining with the lymphatic specific marker LYVE-1, was significantly increased around MM (10.0±2.5 mm−2) compared with normal dermis (2.4±0.9 mm−2), BCC (3.0±0.9 mm−2) and MCC (2.4±1.4 mm−2) (P<0.0001). The gene discussed is LYVE1; the disease is Miyoshi myopathy.