We confirmed a number of ovarian cancer genes previously identified by GEM, for example, CD24 (Welsh et al, 2001), HE4 (Schummer et al, 1999), PRAME (Ismail et al, 2000), B-factor (properdin) (Shridhar et al, 2001), and, where our studies overlap, the data are highly consistent, despite the difference in methodology. Here, PRAME is linked to ovarian cancer.