Although the presence of TP53 mutations did not seem to influence the disease-free survival significantly in early stage of ovarian carcinomas, patients with wild-type TP53 gene had around 15% higher survival rate than patients with mutant TP53 gene after 5 years, which is in agreement with previous studies (Auer et al, 1996). The gene discussed is TP53; the disease is ovarian carcinoma.