There was no correlation between SLIT2 methylation and 1p allele loss (22% of SLIT2 methylated and 22% of unmethylated tumours, P=1.0), 3p allele loss (25 vs 12%, P=0.57), 17q gain (50 vs 65%, P=0.62) or N-myc amplification status (15 vs 13%, P=1.0). This evidence concerns the gene MYCN and neoplasm.