The mean hScrib/GAPDH mRNA level analysed by the quantitative RT–PCR in all cervical neoplastic tissues and normal control tissues did not show a significant difference in normal cervical tissue (1.40±0.15), L-SIL (1.42±0.21), and H-SIL (1.33±0.08), except for the invasive cancer (0.31±0.16). The gene discussed is SCRIB; the disease is squamous cell intraepithelial neoplasia.