ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive: Inhibition of heat shock protein, hsp90, and histone deacetylase results in degradation of BCR-ABL and induction of apoptosis in imatinib-resistant CML cell lines and shows synergism with imatinib (Schad et al, 2002; Nimmanapalli et al, 2003).