Analyses using families with hereditary prostate cancer (HPC) have suggested that multiple genetic loci may harbour prostate cancer susceptibility genes, including HPC1 (MIM 601518) at 1q24–q25, HPC2 (MIM 605367) at 17p11, PCAP (MIM 602759) at 1q42–q43, HPCX (MIM 300147) at Xq27–q28, CAPB (MIM 603688) at 1p36, and HPC20 (MIM 176807) at 20q13 (Nwosu et al, 2001). Here, ELAC2 is linked to prostate cancer.