In this report we determined in parallel the sensitivities of five pancreatic carcinoma cell lines, Capan1, Colo357, PancTuI, Panc89 and Panc1 to anti-CD95- and TRAIL-mediated apoptosis in the context of the cell surface expression of the corresponding receptors. The gene discussed is TNFSF10; the disease is exocrine pancreatic carcinoma.