Using multiple techniques, including in situ hybridisation for FasL mRNA and immunodetection for FasL protein using a variety of different FasL-specific antibodies, FasL expression by colon cancer has been demonstrated both in vivo and in vitro (Shiraki et al, 1997; O'Connell et al, 1998; Mann et al, 1999; Yoong et al, 1999). The gene discussed is FASLG; the disease is malignant colon neoplasm.