NFKB1 and neoplasm: We also confirmed these findings in vivo, as injections of exogenous recombinant hGH in U937 tumour-engrafted nude mice led to increased tumour cell death together with decreased translocation of NF-κB in cell nuclei, in response to subtoxic doses of daunorubicin, an anthracycline agent activating NF-κB in our cells (Cherbonnier et al, 2002).