Subsequently, with that CTL line, we extended our study to identify antigenic epitopes capable of binding to HLA-B4601 allele; we report in this study that heat shock cognate protein 70 (HSC70) gene encodes two nonmutated nonapeptides with the ability to induce HLA-B4601-restricted and tumour-reactive CTLs from cancer patients. Here, HSPA8 is linked to neoplasm.