Vascular endothelial growth factor-1 binds VEGFR-1 (flt-1) but not VEGFR-2 (KDR) (Olofsson et al, 1998), both of which are present in peritumoral endothelial cells of endometrial cancers (Guidi et al, 1996). The gene discussed is FLT1; the disease is endometrial cancer.