CDH1 and cancer: A variety of studies regarding the relationship between the expression of E-cadherin, α-catenin, β-catenin and the existence of lymph node metastasis in human cancers have been performed and some authors found a significant correlation (Sato et al, 1999; Zheng et al, 1999), while others did not (Mattijssen et al, 1993; Andrews et al, 1997).