In addition, expression of EGFR and HER-2/neu is associated with the aggressiveness of an uterine endometrial tumour, and expression of PCNA and Ki67 is correlated with clinical outcome (Khalifa et al, 1994; Niikura et al, 1995; Nordstrom et al, 1996; Fujiwaki et al, 1999; Rolitsky et al, 1999). Here, MKI67 is linked to endometrium neoplasm.