Relative level of SOCS-1 (Figure 3A), SOCS-2 (Figure 3B), SOCS-3 (Figure 3C) and CIS (Figure 3D) mRNA expression was measured densitometrically on autoradiographic films on normal and pathologic breast sections, in areas selected as defined in Materials and Methods. Here, SOCS3 is linked to in situ carcinoma.