Even though correlation of p53 protein expression with clinical and biological characteristics of lung cancer has been extensively studied, the results of these studies are quite diverse (Top et al, 1995; Passlick et al, 1995; Dalquen et al, 1996; Lee et al 1999; Garinis et al, 2001; Zienolddiny et al, 2001). The gene discussed is TP53; the disease is lung cancer.