Therefore, TPTE/BJ-HCC-5 mRNA was expressed as two isoforms: one was identical to TPTE, which encoded a protein of 551 amino acids, called TPTE/BJ-HCC-5A, and the other was the alternative splice variant of TPTE, which lacked the sequence of an exon (54 bp) and encoded a protein of 533 amino acids, lacking 18 amino acids at the position of 41–58 in the NH2-terminus of TPTE, called TPTE/BJ-HCC-5B (GenBank Accession Number AF495908). The gene discussed is TPTE; the disease is hepatocellular carcinoma.