As SF-1 and WT1 are involved in the development of tumour (Bamberger et al, 1996; Menke et al, 1998; Lopez et al, 1999; Sugiyama, 2001; Aylwin et al, 2001; Oka et al, 2002), the FATE/BJ-HCC-2 may also be involved in tumourigenesis. This evidence concerns the gene SF1 and neoplasm.