A number of reports have indicated that FAK may be up-regulated in human tumour cells of diverse origin (Weiner et al, 1993; Akasaka et al, 1995; Owens et al, 1995; Tremblay et al, 1996; McCormack et al, 1997; Cance et al, 2000). The gene discussed is PTK2; the disease is neoplasm.