TP53 and urinary bladder cancer: To confirm the correlation between p53 status and susceptibility to E1B-55 kD-deleted adenovirus, BFTC-905 cell line and its derivative BFTC-173-12 transfectant, in which p53 function has been ablated by expression of a dominant-negative p53 allele, were used in parallel to determine the susceptibility of the bladder cancer cells to Ad5WS1-induced cytolysis.