We have previously shown that 70 – 90% of Min adenomas express MMP-7 in the neoplastic epithelium (Wilson et al, 1997; Shattuck-Brandt et al, 1999) and that Min mice null for MMP-7 have 58% fewer tumours than Min mice with wild-type MMP-7 (Wilson et al, 1997). Here, MMP7 is linked to adenoma.