The U-118 MG cells stably transfected with hCAR-tailless likewise showed a significant decrease in tumorigenicity relative to the parental cells (P<0.01 on day 14; P<0.05 on day 21), whereas no inhibition in tumour growth was observed with the cells stably transfected with hCAR-GPI (P>0.05 on days 14 and 21). The gene discussed is CXADR; the disease is neoplasm.