HMGA2 and neoplasm: These findings and studies on HMGI-C expression in a variety of tumours (Chiappetta et al, 1995; Kazmierczak et al, 1996,1998; Staats et al, 1996; Rogalla et al, 1997,1998; Rommel et al, 1997; Giannini et al, 1999; Klotzbucher et al, 1999) have substantiated the important role of HMGI-C in the control of cell growth, differentiation and tumorigenesis.