CDH2 and neoplasm: This kind of adhesion of N-cadherin was suggested to play important roles in various biological behaviours, including morphogenesis (Takeichi, 1991) and angiogenesis (Gerhardt et al, 1999, 2000) during development and epithelial–mesenchymal transition during tumour progression (Islam et al, 1996; Tran et al, 1999).