In this paper, we describe the construction, expression, and characterisation of a number of fusion proteins between VEGF and CPG2 that can bind to recombinant VEGFR2, and can differentiate between human umbilical vein endothelial cells (HU-V-EC) that express VEGFR2 and human ovarian adenocarcinoma cells (SK-OV-3) that do not. This evidence concerns the gene KDR and ovarian adenocarcinoma.