Upregulation of MMP-2 is seen in solid tumours including hepatocellular (Maatta et al, 2000), colorectal (Liabakk et al, 1996; Baker et al, 2000; Waas et al, 2002) and ovarian cancers (Lengyel et al, 2001). This evidence concerns the gene MMP2 and ovarian carcinoma.