ERBB2 and breast carcinoma: The scFv(ErbB-2)/ζ fusion gene was stably expressed in murine T lymphocytes that subsequently could recognise and lyse either mouse cell lines transfected to express the human ErbB-2 receptor or the human breast cancer MDA-MB453 cell line constitutively expressing ErbB-2 (Moritz et al, 1994; Altenschmidt et al, 1997).