In a more recent analysis of 164 BRCA2 mutation-bearing families (Thompson et al, 2001), 23.8% of tumours were ovarian (and 76.2% breast) among families with OCCR mutations: for families with mutations 5′ and 3′ of the OCCR, 8.8 and 9.6%, respectively, were ovarian cancers. This evidence concerns the gene BRCA2 and ovarian cancer.