When stratified for fascin levels of immunostaining, adenocarcinomas with high (>60%) fascin immunoreactivity exhibited more pronounced proliferative activity (mean±s.d.: 27.9±16.5%; median: 27%) than tumours with negative to low (up to 30%) fascin immunoreactivity (mean±s.d. The gene discussed is FSCN1; the disease is neoplasm.