Based on the rounded regression coefficients (log hazard ratios in the final Cox model) of variables, we defined the weights of prognostic features as follows: neutrophil count was assigned weight 2, the remaining variables (serum level of CRP and LDH, time between diagnosis of tumour and metastatic disease, number of metastatic sites, bone metastases) were given weight 1. Here, CRP is linked to neoplasm.