NFKB1 and neoplasm: Other studies have shown that disruption of NF-κB signalling by transfection with the super-repressor IκBα (Wang et al, 1996; Miyakoshi and Yagi, 2000), by indomethacin (Bradbury et al, 2001) or by the proteasome inhibitors MG-132 and PS-341 (Pajonk et al, 2000; Russo et al, 2001) enhances the radiosensitivity of tumour cells.