NCOA3 and breast neoplasm: Although the relative expression of OR coregulators SRA, AIB1 and ROA is altered between normal breast and OR+ breast tumours, there were no significant differences in the ratios of any of the coactivators/corepressors or any of the ratios of these coregulators to ORα RNA levels between primary breast tumours from patients who were later found to be disease free (sensitive) or have disease progression (resistant) while on adjuvant tamoxifen treatment.