TP53 and neoplasm: Tumour stage (adjusted odds ratio, 3.3; 95% confidence interval 1.3–8.6; P=0.01), node stage (adjusted odds ratio, 2.8; 95% confidence interval 1.2–6.5; P=0.02), p53 wild-type gene status (adjusted odds ratio, 3.9; 95% confidence interval 1.6–9.0; P=0.002), and bcl-2 protein expression in at least 10% of tumour cells (adjusted odds ratio, 26; 95% confidence interval 1.2–559; P=0.04) were also positively associated with response in this model.