When comparing the different methods to evaluate the prognosis of breast cancer, the predictive value of histological grading has been found to exceed that of hormone receptor status, DNA content, and c-erbB-2 or p5+3 expression (Fisher et al, 1988; Merkle et al, 1993; Macgrogan et al, 1995; Quenel et al, 1995). Here, NR4A1 is linked to breast cancer.