Deficiencies of its metabolic precursor Filaggrin, have been shown in the lower leg of elderly citizens.7 Bedridden status is known to significantly reduce the stratum comeum water content among older people.8 Furthermore, long-term vitamin C insufficiency may also lead to dermatological abnormalities such as dry, scaly skin.9 Our study revealed xerosis as the most common skin disease present among the patients studied, affecting almost one-third of them (29.5%). This evidence concerns the gene FLG and Dry skin.