INS and diabetes mellitus: Electrofusion-derived BRIN-BD11 cells are glucosesensitiveinsulin-secreting cells which provide anarchetypal bioengineered surrogate β-cell forinsulin replacement therapy in diabetes mellitus,5x106 BRIN-BD11 cells were implanted intraperitoneallyinto severely hyperglycaemic (>24mmol/l)streptozotocin-induced insulin-treated diabeticathymic nude (nu/nu) mice.