RHO and neoplasm: In the present study we aimed at (1) analysing the expression of different members of the family of Rho GTPases in breast tumours, both on the level of the protein and the mRNA, (2) establishing whether a correlation between Rho expression and clinically established diagnostic and prognostic parameters does exist and, (3) investigating whether or not Rho GTPases are mutationally altered in tumours.