VEGFC and neoplasm: It has recently been demonstrated that primary solid tumours expressing vascular endothelial growth factors -C and -D (VEGF-C and -D), induce lymphangiogenesis de novo, thereby providing a direct conduit for tumour cell dissemination to lymph nodes (Mandriota et al, 2001; Skobe et al, 2001; Stacker et al, 2001).