In addition, ectopic expression of Fas-L in transgenic animals or tumours revealed that Fas-L enhanced neutrophil recruitment and mediated destruction of certain Fas-L-positive cells (Arai et al, 1997; Chervonsky et al, 1997; Seino et al, 1997; O'Flaherty et al, 1998). The gene discussed is FASLG; the disease is neoplasm.