The tumours grouped in CIM areas A to C were resistant as well, but they showed a different protein expression profile compared to the resistant tumours of CIM areas D to F. These NSCLC exhibited a rather low expression of drug resistance genes (except MGMT and GSTP1; CIM area A) and proliferation/angiogenesis-regulating proteins (CIM areas B and C). The gene discussed is GSTP1; the disease is neoplasm.