TP53 and cancer: One of the major defects in cancers is the lack of cells to be driven into the apoptotic mode, due to malfunction of molecules like c-myc (Evan and Littlewood, 1998), ras (White et al, 1995), p53 (Soengas et al, 1999), bcl2 (Haldar et al, 1995), caspases (Schotte et al, 2001) and telomerase (Shay and Bacchetti, 1997).