p27 expression in endometrioid adenocarcinomas was not associated with hormone-related clinicopathological situations such as menopause, Group (Group 1: coexisting with endometrial hyperplasia, Group 2: coexisting with normal endometrium, Group 3: entirely replaced by carcinoma) (Ohkawara et al, 2000), and expression of ER or PR, although it was reportedly mediated by a progesterone-related hormonal environment in normal endometrium (Shiozawa et al, 1998). This evidence concerns the gene PGR and carcinoma.