On the other hand, tumour cells have been shown to produce other angiogenic factors such as bFGF (Abraham et al, 1986; Gospodarowicz et al, 1987), TGF-α (Smith et al, 1987) and PDGF (Holmgren et al, 1991; Risau et al, 1992). Here, FGF2 is linked to neoplasm.