TYMP and cancer: In all cases, however, high TP expression was associated with high angiogenesis, irrespective of the main source of TP production, and this was confirmed by further studies in endometrial and in non-small cell lung tumours, where cancer cells and stromal fibroblasts were independently associated with high angiogenesis (Koukourakis et al, 1998; Sivridis et al, 2001).