Several studies evaluated HER-2/neu oncogene and protein expression in lung cancers using immunohistochemical (IHC) techniques (Schneider et al, 1989; Kern et al, 1990; Tateishi et al, 1991; Paakko et al, 1992; Tsai et al, 1993; Hsieh et al, 1998). This evidence concerns the gene ERBB2 and lung cancer.