In the control subjects, IL-6 level was 1.79±2.03 pg ml−1, TNFα level was 2.74±0.94 pg ml−1 and IL-1β level was 0.16±0.17 pg ml−1, while in the RCC patients, IL-6 level was 8.91±13.12 pg ml−1, TNFα level was 8.44±4.15 pg ml−1 and IL-1β level was 0.53±0.57 pg ml−1 and significantly higher (IL-6: P<0.05, TNFα: P<0.0001, IL-1β, P<0.05). Here, TNF is linked to renal cell carcinoma.