GRP and glioblastoma: In view of findings that 85% of human glioblastoma cell lines express functional receptors for BN/GRP (Moody et al, 1989; Staley et al, 1993; Pinski et al, 1994; Sharif et al, 1997), we evaluated in this study the efficacy of targeted chemotherapy based on cytotoxic analogue of BN, AN-215 in U-87MG human glioblastoma xenografted into nude mice.